Brad will then provide an overview of the company's fourth quarter and full year 2025 financial results, and Terry will make some introductory comments. Earlier today, we issued a press release detailing the full year 2025 financial results and summarized certain achievements and recent corporate updates. Please note that the discussion on today's call includes certain non-GAAP financial measures, including adjusted EBITDA and adjusted net income. A reconciliation of these non-GAAP financial measures to the most directly comparable GAAP metric is available in our earnings release.

For the full year, total revenue was $510 million, representing 20% year-over-year growth. Adjusted EBITDA was $231 million, increasing 40% year-over-year, and adjusted net income was $161 million, increasing 35% year-over-year. These results underscore the durability of our growth engine and the expanding operating leverage within our fully integrated U.S.-based business model. We expanded margins, improved our balance sheet, and executed several strategic initiatives that enhanced the long-term durability and earnings power of our company as we enter the next phase of growth.

For full year 2025, Asceniv achieved $363 million in net revenue, representing 51% year-over-year growth. Our differentiated, patent-protected specialty immune globulin exited the year at record utilization levels, driven by high demand and strong prescriber adoption. Before turning to additional operating highlights, I want to briefly address working capital. As demand builds and our McKesson distribution agreement ramps up, alongside further anticipated diversification of our distribution network, we expect improving working capital efficiency and cash conversion throughout 2026.

What went well
  • Record full-year 2025 results: revenue $510 million (up 20%), adjusted EBITDA $231 million (up 40%), and adjusted net income $160.8 million (up 35%).
  • Strong fourth quarter with revenue of $139.2 million (up 18% year-over-year), adjusted EBITDA of $73.6 million (up 52%), and adjusted net income of $52.6 million (up 57%).
  • ASCENIV full-year revenue reached $363 million, up 51% year-over-year, exiting the year at record utilization.
  • Gross margin expanded to 57.4% for the full year (from 51.5%), with fourth-quarter corporate gross margin of 63.8%.
  • A strategic plasma-center monetization (selling three centers, retaining seven, and adding supply agreements giving access to over 280 centers) improved capital efficiency and long-term high-titer supply visibility.
  • Raised multi-year guidance: 2026 revenue above $635 million, 2027 above $775 million, and 2029 above $1.1 billion with adjusted EBITDA above $700 million.
What went wrong
  • The company announced a CFO transition, with Brad Tade retiring and moving to a consulting role through July 2026.
  • Elevated working capital, accounts receivable and days sales outstanding reflected rapid ASCENIV growth, with management targeting improvement over 2026.
  • The company ended 2025 with only $88 million in cash, largely excluding proceeds from the pending plasma-center divestiture.
  • The plasma-center divestiture had not yet closed and remained on track only for the first quarter of 2026, leaving proceeds pending.
  • Broader standard-IVIG market dynamics persisted as a headwind that ASCENIV had to grow through.

More on Adma Biologics, Inc.

Reported 2026-02-25 · figures from the Adma Biologics, Inc. Q4 2025 earnings call.

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